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apalutamide will lower the extent or impact of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with drugs that happen to be CYP2C19 substrates can result in lower publicity to these remedies.Ahead of use, instruct individual administering diazep